What are the causes of Alzheimer’s Disease and related dementia? How do they cause neurodegeneration and dementia?
Credit: Gabriel Luna
What are the causes of Alzheimer’s disease and related dementias? What are the molecular mechanisms underlying their destructive actions? Can we identify novel targets or strategies for possible therapeutic intervention?
Dr. Acevedo’s research focuses on the neural and genetic basis of attachment and sensory processing sensitivity (and related disorders), and mind-body interventions.
The Han lab uses advanced electron and nuclear magnetic resonance spectroscopy tools to pursue the study of biomolecular structure, molecular interactions, dynamics and functional processes with atomic and molecular-level insight.
The goal of our lab is to build useful gadgets. Current projects include multi-electrode probes for neuron cell cultures and multi-sensor biofeedback devices to help people overcome chronic pain.
Mechanism and regulation of microtubule polymerization and dynamics; mechanism of action of microtubule-targeted anticancer drugs and microtubule-regulatory proteins.
Neural plasticity including the molecular basis of plasticity, the evolution of synapses, and disease-related impairments of plasticity such as occurs in Alzheimer's disease.
Molecular mechanisms of signal transduction; Alzheimer's Disease and other protein aggregation/misfolding diseases; molecular biology, enzymology, and protein structure/function.
Mechanism and regulation of microtubule polymerization and dynamics; mechanism of action of microtubule-targeted anticancer drugs and microtubule-regulatory proteins.